Pioneering the Longevity Revolution

TRANSFORMING SYSTEMIC INFLAMMATION ~ THE BIOLOGY BEHIND MOST ALL disease ~ with FIRST-In-CLASS immuno-regulators.

Inflammation underlies more than 75% of modern disease. Yet today’s treatments are late, reactive, and narrow—delivering limited benefit at immense cost.  Keeping the gap between lifespan and healthspan at an all time high.

At Sen-Jam, we combine deep biology with AI-driven insights to accelerate solutions that rewrite this story. Our PAIR immuno-regulator platform applies a simple but powerful therapeutic logic: address inflammation at its biological root with unmatched safety, scalability, and accessibility.

By directly modulating the immune system—rather than chasing symptoms—we are defining a new class of medicine. One that bridges prevention, longevity, and recovery. One that extends healthspan while reducing the crushing global burden of chronic disease.

Sen-Jam isn’t just improving care. We’re reframing how the world thinks about health itself—turning immuno-regulation into the foundation of the next era in preemptive healthcare.

What We Believe

What If We’ve Been Solving the Wrong Problem?

For decades, medicine has chased symptoms—while unchecked inflammation quietly drives disease from the inside out. Discover how one Pharmacist’s bedside insight sparked a new path forward.

A Trillion-Dollar Lever for Global Health

When you resolve inflammation at its source, you don’t just ease symptoms—you alter the course of disease itself. The ripple effect is profound: reduced suffering, extended healthspan, and a rebalanced healthcare economy.

Sen-Jam’s PAIR platform is designed to unlock this shift. Our lead assets target four of the world’s most devastating and costly health burdens—conditions that collectively drain trillions from societies and economies every year.

By moving upstream, we’re not only redefining how these diseases are treated, but also transforming the very economics of global health.

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Metabolic Overload (overeating, obesity, alcohol-related stress)

$4.3 trillion—projected 3% of global GDP by 2035

The world’s most costly daily habit—reshaping metabolism, accelerating disease.

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Opioid Crisis (withdrawal, dependence, tolerance)

$2.7 trillion U.S. impact in 2023 alone 

A trillion-dollar hemorrhage—where safer, inflammation-driven, non-opioid solutions are urgently needed.

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Respiratory Infections (COPD, URIs, COVID, RSV)

#3 global cause of death; 3.2 million COPD deaths/year  

Every breath carries a toll—where unchecked inflammation turns treatable illness into tragedy.

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Runaway Hospital Inflammation (Sepsis, ARDS, critical-care inflammation)

11 million deaths and $52B U.S. spend per year 

In the ICU, it’s the silent driver of cost, mortality, and system strain.

PAIR turns these towering costs into opportunity—quietly, elegantly, with a safety profile we are actively proving to be a mechanism ready to reshape global health.
Next—meet the combination duo unlocking this new frontier

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Two Proven Molecules, One Novel Alliance

PAIR repurposes a decades-trusted NSAID and a well-characterized mast-cell modulator, tuning their ratios so they work with—rather than against—your innate immune sentinels. By soothing mast cells while dampening COX1 and COX2 in the same breath, this dynamic duo halts the inflammatory cascade upstream, turning familiar chemistry into breakthrough, tissue-sparing relief.

When one elegant alliance can be tuned like a dial, opportunity multiplies fast. Scroll on to see how the same PAIR blueprint is already branching into eleven tailored programs—some headed for the pharmacy aisle, others for the ICU—all advancing our pipeline.

Therapeutic Pipeline

Addressing Significant Unmet Needs with a Revolutionary Combination Immuno-Inflammatory Portfolio

Icon Rx  Prescription Strength Relief

Icon Otc  Over the Counter Relief

Discovery
Screening
Preclinical
Phase 1
Phase 2
Phase 3

Upper Respiratory Infections, including COVID

Obesity/MASH

SJP-002C Mild to Moderate URI infection + Treatment in Obesity/MASH - Oral
SJP-100 Critical-Care Rescue - Injectable

Metabolic Recovery (food and alcohol)

SJP-001 Metabolic Rebalance & Recovery - Oral

Opioid Use Disorder

SJP-005 Opioid Withdrawal - Oral
SJP-006 Opioid Dependence - Oral
SJP-007 Opioid Tolerance - Oral

Vaccination Side-effects

SJP-003 Adverse Effects from Vaccine - Oral

Respiratory Common Cold

SJP-002 Viral Respiratory Infection - Oral

Arthritis

SJP-004 Arthritis - Oral
SJP-101 Arthritis - Injectable

Premature Aging

SJP-200 Low-grade Chronic Inflammation - Oral

Icon Rx  Prescription Strength Relief

Icon Otc  Over the Counter Relief

COVID-19/URI
SJP-002C SARS-CoV-2-Mild to Moderate infection - Oral
PHASE 2
SJP-100 SARS-CoV-2-Severe infection - Injectable
PRECLINICAL
Adverse Effects of Alcohol
SJP-001 Alcohol Hangover Prevention - Oral
PHASE 1 END
OPIOID USE DISORDER
SJP-005 Opioid Withdrawal - Oral
PHASE 1 END
SJP-006 Opioid Dependence - Oral
Preclinical
SJP-007 Opioid Tolerance - Oral
Preclinical
VACCINATION SIDE-EFFECTS
SJP-003 Adverse Effects from Vaccine - Oral
Preclinical
UPPER RESPIRATORY INFECTIONS
SJP-002 Viral Respiratory Infection - Oral
PHASE 1
ARTHRITIS
SJP-004 Arthritis - Oral
Preclinical
SJP-101 Opioid Withdrawal - Injectable
Preclinical
Premature Aging
SJP-200 Low-grade Chronic Inflammation - Oral
Preclinical

World-Class Expertise Driving a New Standard of Care

Our leadership, scientific advisors, and collaborators draw on experience and active engagements across many of the world’s most respected institutions—helping bring Sen-Jam’s vision to the forefront of inflammation science and translational medicine.

Rewriting the Future of Inflammatory Care

Be part of a new chapter in medicine—where upstream solutions preserve healthspan, transform outcomes, and redefine the economics of disease.

Help us change the course of global health.
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